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Research Officer

Murdoch Childrens Research Institute

Who We Are

Murdoch Children’s Research Institute (MCRI): At MCRI we share a powerful vision; to re-imagine the future of child health. We are the home to many life-changing scientific discoveries. We believe that no question is too impossible to try and answer.

We are renowned for our cutting edge focus on early interventions, improved diagnosis, prevention and development of potential cures. Our success is founded on a philosophy of collaboration through a multi-disciplinary approach to solving the toughest questions in child health.

MCRI is committed to creating a culture of inclusivity, equity and respect that celebrates and values the diverse backgrounds and experiences of our people.

We strive to foster a positive working environment that is underpinned by equal opportunity for all and consideration for the diverse voices of staff, students and the communities we serve. MCRI is a proud member of the Australian Network on Disability and is a committed subscriber to Science Australia Gender Equity and its principles.

The Opportunity at MCRI:

This is an exciting opportunity for a talented and highly motivated researcher with a strong interest in biochemical signalling and proteomics to join the Neuro-oncology group led by Prof David Eisenstat at MCRI.

Our research aims to discover new transcriptional regulatory mechanisms and characterise these at the molecular and genomic level in normal development and in cancer. Our research combines advanced genomics and proteomic technologies and bioinformatic analysis with cell biology, iPSC/3D brain organoid culture systems and biochemical signalling. Thanks to the Live for Lily foundation, we have the opportunity to study the biochemical signalling mechanisms that regulate the distal-less (DLX) transcription factor in brain development.

The overall goal of this ECR research project is to discover the mechanisms that activate (“turn on”) or block (“shut off”) DLX2 by characterising key amino acid residues required for DLX2 function in brain development, in addition to identifying the critical signalling pathways in brain development and DIPG tumours.

To be successful in this role you possess a PhD in a relevant discipline and have a strong publication track record. You will also be required to have experimental expertise in protein biochemistry and proteomics. This role will suit an enthusiastic and motivated individual with an independent work ethic and willingness to work in a collaborative environment. You will possess excellent communication and interpersonal skills with the ability to present research at conferences and write for scientific publications.

Your Responsibilities will include:

  • Developing detailed and thorough knowledge of own and related subject areas, including the latest scientific research
  • Actively searches for relevant new techniques and builds expertise in specific research field
  • Planning and carries out research under limited supervision which may involve experimental design, as sole researcher or as part of a multidisciplinary collaboration
  • Conducts ethical research at the highest level of integrity and in line with the Australian Code for Responsible Conduct of Research and MCRI policies

About You:

  • Relevant PhD/Doctoral qualification
  • An excellent academic record and achievements
  • Experience in protein biochemistry and proteomics
  • Excellent time management, organisational and analytical problem-solving skills

How to Apply!

You are invited to apply online via the MCRI Careers Portal, via the Apply Now link.

Applicants should submit:

For more information, please refer to the position description (also attached below).

Any specific questions related to this position should be directed to Prof David Eisenstat at [email protected], using the subject line: Research Officer enquiry via EthicalJobs.

We welcome all genders, ages, ethnicities, cultural backgrounds, abilities, religions and sexual orientations in our workplace and encourage talented people of any identity to apply to our vacancies. We will provide reasonable adjustments in our recruitment process and in the workplace, please contact the People Leader listed above if this is needed.

All applicants, please be aware that in line with the Victorian Chief Health Officer’s Directions, all MCRI and VCGS workers must be fully vaccinated, unless a medical exception applies. Applicants will be required to provide their Australian Government COVID-19 Digital Immunisation Certificate/s or evidence of medical exception or evidence of vaccination booking as part of our pre-employment requirements.

Please note, we reserve the right to close the vacancy prior to the closing date once a sufficient number of applications have been received.

How to apply

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